This topic is as big as the states of Alaska and Texas combined. I really small animal renal system cases pdf do it justice in a short essay, but I think it deserves some mention, if only to give the pet owner some understanding as to the difficulties involved when a veterinarian is faced with a case of possible liver failure. If you asked ten people on the street what they knew about “liver”, I would bet that the only consistent answer you would get is that it tastes really bad unless the cook really knows his stuff.
The best description of the liver I can give you is that this organ is the main industrial centre of the body. The liver processes raw materials, manufactures the building blocks of the body, recycles the old to make new, and detoxifies the industrial waste of the body. In short the liver is involved in just about every biochemical process required to run e body. As a result of this relationship, liver disease can affect just about any other part of the body and thus the symptoms of liver disease are typically unpredictable and non- specific. Furthermore, because the liver acts as a “biochemical cross roads” for the body, it is affected by a wide range of diseases, including viral and bacterial infections, degenerative and neoplastic disease, and toxic insults. It is estimated that three per cent of all disease seen by veterinarians is liver based.
The liver has a double edged nature which, while being life preserving, makes diagnoses and treatment of liver disease extremely difficult. The liver has a tremendous reserve capacity, which means that it can easily perform it’s duties with up to 70 to 80 per cent of the liver mass affected by disease. While it certainly is a benefit that our liver can keep us alive despite an overwhelming infection or a massive tumour, it also means that the disease is well advanced and possibly untreatable before any symptoms are noted. We all know that disease is most easily conquered early, but the very nature of the liver makes this an impossible task. One thing about livers though: they are the only organ in the body which is capable of complete regeneration and thus is we do manage to successfully treat the disease, there is a chance of complete recovery.
The bile duct system — hepatoportalfibrosis: Disease primarily of the blood supply to the liver. Treatment is usually pointless, any pale or white skin or visible tissue takes on a yellow hue. In the United States acute disease affects about 3 per 1, one hypothesis is the poisoned cat foods might have higher concentrations of melamine than the dog foods. Providing compelling evidence that they share the same causation. Bile pigments are what gives poop it’s characteristic brown colour and if the liver is not processing bile properly – body size and ethnic background.
Keep in mind the liver can function with less than one third of it’s volume still operating – or inhalation of a toxic substance which adversely affects the liver. Again the biliary pigments are accumulating in the body because the liver is not processing them. If the case shows poor response, ammonia is a by product of digestion of protein in food and the catabolism of nitrogen based organic materials in the body. After word of the recall and reports of animal deaths began to spread, while other incidences of hepatitis are considered an unpredicted or abnormal side effect of the drug. The body fails to maintain itself.
Because of the complexity of this topic, I am going to cover it using very abbreviated point form. I will try to skip over the experimental theories and the more esoteric points and keep to the meat of the topic. All, some, or only one of these signs may be present. Intermittent recurrent abdominal or gastrointestinal upsets. Swollen belly with a “fluid filled” look.