Control of hyperplastic and invasively growing gingival tissue is crucial for maintaining normal oral function and for successful bone regenerative therapy. To simulate inflammatory nac nacetyl cystine study pdf, cultures were treated with hydrogen peroxide.
NAC was also applied via collagen materials in membrane and sponge forms to explore the clinical applicability. Adding NAC into cultures of oral mucosal cells reduced their proliferation, transcriptional expression, and collagen production in an NAC-concentration-dependent manner without cytotoxic effects. Furthermore, NAC substantially reduced the hydrogen peroxide-induced elevation of cellular proliferation and collagen production. These results indicate that NAC may abrogate inflammation- or oxidative-stress-induced hyperfunction of oral mucosal cells and that it can be delivered effectively via biodegradable materials. This study provides a basis to explore NAC-containing biomaterials that are functionalized to control oral soft tissue growth and function without cytotoxicity. Check if you have access through your login credentials or your institution.
2009 Academy of Dental Materials. Find patient medical information for N-ACETYL CYSTEINE on WebMD including its uses, effectiveness, side effects and safety, interactions, user ratings and products that have it. Vitamin Supp Brand Prod Reviews Mono Frameworks_091e9c5e806e3bb7_tsmodules_css_208. Vitamins Supplements Frameworks Main Template_091e9c5e806e2fee_tmodules_css_51. Vitamins Supplements Frameworks Main Template_091e9c5e806e3db265.
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